3D Brain development model that recapitulates the developmental molecular programs of human brain from human astrocytes that contain neural stem cells. All cortical neuronal subtypes are formed and reach to a mature electrophysiological stage. This model is suitable for applications that require reliable human brain development systems. These include but not limited to neurodevelopmental diseases and toxicity screening (PK/PD studies, hit-to-lead optimization, efficacy studies).
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