3D-AD

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3D Alzheimer's Disease model that mimic the human pathophysiology after amyloid toxicity. Phenotypes include synaptic degeneration, loss of neuronal connectivity, cell death, de novo TAU hyperphosphorylation, tangle formation, impaired axonal tracks, loss of cortical neuronal marker expression and reduced neural stem cell proliferation and neurogenesis. This model is one of its kind for testing the early pathological aspects of Alzheimer's disease in a reductionist neuronal environment. With its high degree of customizable nature, we can offer a flexible range of product specifications based on your needs. With our versatile readout portfolio, this system is unique in many ways!